Booze calories nearly equal soda's for US adults

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NEW YORK (AP) — Americans get too many calories from soda. But what about alcohol? It turns out adults get almost as many empty calories from booze as from soft drinks, a government study found.

Soda and other sweetened drinks — the focus of obesity-fighting public health campaigns — are the source of about 6 percent of the calories adults consume, on average. Alcoholic beverages account for about 5 percent, the new study found.

"We've been focusing on sugar-sweetened beverages. This is something new," said Cynthia Ogden, one of the study's authors. She's an epidemiologist with the Centers for Disease Control and Prevention which released its findings Thursday.

The government researchers say the findings deserve attention because, like soda, alcohol contains few nutrients but plenty of calories.

The study is based on interviews with more than 11,000 U.S. adults from 2007 through 2010. Participants were asked extensive questions about what they ate and drank over the previous 24 hours.

The study found:

—On any given day, about one-third of men and one-fifth of women consumed calories from beer, wine or liquor.

—Averaged out to all adults, the average guy drinks 150 calories from alcohol each day, or the equivalent of a can of Budweiser.

—The average woman drinks about 50 calories, or roughly half a glass of wine.

—Men drink mostly beer. For women, there was no clear favorite among alcoholic beverages.

—There was no racial or ethnic difference in average calories consumed from alcoholic beverages. But there was an age difference, with younger adults putting more of it away.

For reference, a 12-ounce can of regular Coca-Cola has 140 calories, slightly less than a same-sized can of regular Bud. A 5-ounce glass of wine is around 100 calories.

In September, New York City approved an unprecedented measure cracking down on giant sodas, those bigger than 16 ounces, or half a liter. It will take effect in March and bans sales of drinks that large at restaurants, cafeterias and concession stands.

Should New York officials now start cracking down on tall-boy beers and monster margaritas?

There are no plans for that, city health department officials said, adding in a statement that while studies show that sugary drinks are "a key driver of the obesity epidemic," alcohol is not.

Health officials should think about enacting policies to limit alcoholic intake, but New York's focus on sodas is appropriate, said Margo Wootan, director of nutrition policy for the Center for Science in the Public Interest, a public health advocacy group.

Soda and sweetened beverages are the bigger problem, especially when it comes to kids — the No. 1 source of calories in the U.S. diet, she said.

"In New York City, it was smart to start with sugary drinks. Let's see how it goes and then think about next steps," she said.

However, she lamented that the Obama administration is planning to exempt alcoholic beverages from proposed federal regulations requiring calorie labeling on restaurant menus.

It could set up a confusing scenario in which, say, a raspberry iced tea may have a calorie count listed, while an alcohol-laden Long Island Iced Tea — with more than four times as many calories — doesn't. "It could give people the wrong idea," she said.

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Online:

CDC report: http://www.cdc.gov/nchs/

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FBI veteran started Petraeus email probe

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The FBI agent who investigated harassing emails to a Florida socialite, a probe that set off a chain of events leading to the resignation of CIA director David Petraeus over an extramarital affair, was a veteran investigator who has worked on high-profile terrorism cases.


The agent was identified as Frederick Humphries by a former federal agent, a source familiar with the Petraeus investigation and Humphries' attorney, Lawrence Berger.


Humphries, 47, received the initial complaint from Jill Kelley, 37, a Tampa, Fla., socialite, about "harassing" emails that an investigation traced back to Paula Broadwell, a 40-year-old author who co-wrote a biography of Petraeus, 60.


The investigation ultimately uncovered evidence of an affair between Broadwell and Petraeus, prompting Petraeus to resign last week.


Berger said his client's family "knew the Kelley family socially for several years." Jill Kelley asked Humphries for advice on what she perceived to be threatening e-mails and he "referred the matter to the bureau as appropriate."


Berger said his client has been wrongly characterized as a "whistleblower," but there is "no action pending against him, nor does he anticipate any future action."


Humphries "referred the matter to the FBI in accordance to proper protocol," Berger added, and the FBI investigation is taking its course.


Berger flatly declined to confirm or provide any details at all regarding Humphries' alleged contacts with the offices of either Rep. Dave Reichert, R-Wash., or House Majority Leader Rep. Eric Cantor, R-Va.


According to the New York Times, Humphries was allegedly concerned the case had been stalled for political reasons, and in late October contacted Reichert, whom he knew from his time working in Washington. The Times reported that Reichert put him in touch with Cantor, who then passed the message to FBI director, Robert Mueller.


An associate of Humphries told ABC News that it was hard to believe that Humphries had contacted elected officials about the case because "everyone knows that's professional suicide" and Humphries is "top notch."


Humphries has worked as a supervisor on Joint Terrorism Task Force in Tampa and has worked on high-profile terrorism cases.


In Seattle, Humphries worked the so-called Millenium terror plot in 1999, which prevented an Algerian al Qaeda member from bombing Los Angeles International Airport.


More recently, he testified in Florida in a terrorism case of Florida student Youssef Megahed and his associates.


In that case, back in 2007, a sheriff's deputy with the Berkeley County Sherriff's Office in South Carolina became suspicious when University of South Florida student Ahmed Mohamed and his companion, fellow USF student Megahed, did not initially stop when they were pulled over for speeding. The officer said he saw Megahed disconnect a power cord from a laptop computer as he approached the car. The deputy searched the vehicle. According to court records, he found safety fuses, several sections of cut PVC piping containing a potassium nitrate explosive mixture and containers filled with gasoline.


The pair was arrested that night for transporting explosives. Following the arrest, the FBI in Tampa and South Carolina began an investigation with the Joint Terrorism Task Force.




Regarding a "shirtless" photo that Humphries reportedly sent to Jill Kelley, Berger told ABC News that several years ago, Humphries sent a "joke picture" of himself to the Kelley family showing Humphries "posing shirtless between two shooting range dummies."


"There was absolutely no romantic involvement or relationship whatsoever between Agent Humphries and Jill Kelley," said Berger.


According to Berger, sharing funny photos was part of the family's relationship.


Berger objected to unattributed comments in the New York Times that his client was "obsessed" with pursuing the matter.


"Is he a dogged, professional, passionate law enforcement officer? Yes," Berger told ABC News. But it would be "incorrect to describe him as obsessed" with this case, said Berger.


According to Berger, Humphries "reported what he knew according to FBI protocol and then let the investigation take its course."


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Panetta: Don't jump to conclusions about Allen

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PERTH, Australia (AP) — Defense Secretary Leon Panetta cautioned Wednesday against reaching early conclusions about the veracity of allegations against the top U.S. commander in Afghanistan, Gen. John Allen, who is under investigation for what Pentagon officials have said may be "inappropriate" correspondence with a Florida woman linked to the David Petraeus sex scandal.

At a news conference in Australia's Indian Ocean coastal city of Perth, Panetta sought to tamp down a wave of speculation about the nature of Allen's actions, which have added a new dimension to the Petraeus matter.

"No one should leap to any conclusions here," Panetta said in his first public comments on the matter when a reporter asked what Allen might have done wrong. Panetta declined to characterize Allen's actions in any way.

Panetta said he supports Allen, who has been in command in Kabul since July 2011. He took over that summer for Petraeus, who retired from the Army to head the CIA.

"He certainly has my continued confidence to lead our forces and to continue the fight," Panetta said.

The Pentagon chief declined to explain the nature of Allen's correspondence with Jill Kelley, the Florida socialite connected to the scandal that led to Petraeus' resignation last week as director of the CIA.

Secretary of State Hillary Rodham Clinton, who appeared with Panetta and their Australian counterparts at Wednesday's news conference, declined to comment on the Allen case except to suggest it has not harmed the war effort.

She said U.S. officials have discussed the matter with allied officials.

"There has been a lot of conversation, as you might expect, but no concern whatsoever being expressed to us because the mission has been set forth and it's being carried out," Clinton said.

Panetta announced Tuesday while flying to Australia that he had ordered the Defense Department's inspector general to investigate Allen based on material referred to the Pentagon on Sunday by the FBI. Pentagon officials said the material included at least 20,000 pages of Allen correspondence.

Panetta had also announced Tuesday that the Obama administration put on hold Allen's nomination to be the next commander of U.S. European Command and the top NATO general. Allen's Senate confirmation hearing was to have been held Thursday.

Panetta said in Perth that putting a hold on the nomination was the "prudent" thing to do.

Allen, who was in Washington when Panetta announced the investigation and has not yet returned to his headquarters in Kabul, has not publicly commented on the matter.

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Guilty plea expected by reputed Conn. mobster

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HARTFORD, Conn. (AP) — A 76-year-old reputed Connecticut mobster is expected to plead guilty in a weapons and prescription drugs case that has revealed the FBI's belief that he has information about the largest art heist in history.

Robert Gentile, of Manchester, has a change-of-plea hearing scheduled in Hartford federal court on Wednesday. He has pleaded not guilty to allegations he illegally possessed firearms and explosives and sold illegally obtained prescription drugs.

It's not clear whether there is a plea deal. Gentile's lawyer and a spokesman for the U.S. attorney's office declined to comment about the hearing.

Gentile hasn't been charged in the museum theft. His attorney, A. Ryan McGuigan, has said his client knows nothing about the heist and isn't a Mafia member.

At a court hearing in March, Assistant U.S. Attorney John Durham said the FBI believes Gentile "had some involvement in connection with stolen property" related to a 1990 heist at Boston's Isabella Stewart Gardner Museum.

Thieves disguised as police officers struck as the city finished celebrating St. Patrick's Day, tying up two guards and making off with 13 pieces of art including masterworks by Rembrandt, Vermeer, Degas and Manet worth more than a half-billion dollars. The artwork hasn't been found and the museum is still offering a $5 million reward.

Durham has said that FBI agents had unproductive discussions with Gentile about the theft, but he didn't elaborate on his allegations. Durham also said the FBI believes Gentile is a made member of a Philadelphia crime family.

Gentile has been detained since February when he and an associate, Anthony Parente, were charged with selling illegally obtained prescription drugs including OxyContin, Dilaudid and Percocet.

Authorities searched Gentile's home and reported finding homemade dynamite sticks, several guns, ammunition, homemade silencers, a bulletproof vest, handcuffs, police scanners, brass knuckles and $22,000 in cash at the bottom of a grandfather clock.

Federal agents swarmed Gentile's home again in May in what McGuigan called a veiled attempt to find the stolen paintings. McGuigan said at the time that the FBI got a new warrant allowing the use of ground-penetrating radar to look for buried weapons, but he believed they really were looking for the artwork.

"This is nonsense," McGuigan said in May. "This is the FBI. Are you trying to tell me they missed something the first time? They're trying to find $500 million of stolen artwork. ... All they're going to find is night crawlers."

All McGuigan would say on Tuesday was that Gentile has been confined in a cell by himself and "looks terrible."

"They have him in a hole 24 hours a day where he can't see anybody," McGuigan said.

Gentile is charged with three weapons crimes that each carry up to 10 years in prison and six drug crimes that carry up to 20 years in prison apiece. He wasn't supposed to have any guns because of a 1990s larceny conviction.

The drug case against Parente remains pending. He is free on bail.

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Report: FDA wanted to close Mass pharmacy in 2003

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WASHINGTON (AP) — Nearly a decade ago, federal health inspectors wanted to shut down the pharmacy linked to a recent deadly meningitis outbreak until it cleaned up its operations, according to congressional investigators.

About 440 people have been sickened by contaminated steroid shots distributed by New England Compounding Center, and more than 32 deaths have been reported since the outbreak began in September, according to the Centers for Disease Control and Prevention. That has put the Framingham, Mass.-based pharmacy at the center of congressional scrutiny and calls for greater regulation of compounding pharmacies, which make individualized medications for patients and have long operated in a legal gray area between state and federal laws.

The House Energy and Commerce Committee released a detailed history of NECC's regulatory troubles on Monday, ahead of a meeting Wednesday meeting to examine how the outbreak could have been prevented. The 25-page report summarizes and quotes from FDA and state inspection memos, though the committee declined to release the original documents.

The report shows that after several problematic incidents, Food and Drug Administration officials in 2003 suggested that the compounding pharmacy be "prohibited from manufacturing" until it improved its operations. But FDA regulators deferred to their counterparts in Massachusetts, who ultimately reached an agreement with the pharmacy to settle concerns about the quality of its prescription injections.

The congressional report also shows that in 2003 the FDA considered the company a pharmacy. That's significant because in recent weeks public health officials have charged that NECC was operating more as a manufacturer than a pharmacy, shipping thousands of doses of drugs to all 50 states instead of small batches of drugs to individual patients. Manufacturers are regulated by the FDA and are subject to stricter quality standards than pharmacies.

The report offers the most detailed account yet of the numerous regulatory complaints against the pharmacy, which nearly date back to its founding in 1998. Less than a year later, the company was cited by the state pharmacy board for providing doctors with blank prescription pads with NECC's information. Such promotional items are illegal in Massachusetts and the pharmacy's owner and director, Barry Cadden, received an informal reprimand, according to documents summarized by the committee.

Cadden was subject to several other complaints involving unprofessional conduct in coming years, but first came to the FDA's attention in 2002. Here are some key events from the report highlighting the company's early troubles with state and federal authorities:

__ In March of 2002 the FDA began investigating reports that five patients had become dizzy and short of breath after receiving NECC's compounded betamethasone repository injection, a steroid used to treat joint pain and arthritis that's different from the one linked to the current meningitis outbreak.

FDA inspectors visited NECC on April 9 and said Cadden was initially cooperative in turning over records about production of the drug. But during a second day of inspections, Cadden told officials "that he was no longer willing to provide us with any additional records," according to an FDA report cited by congressional investigators. The inspectors ultimately issued a report citing NECC for poor sterility and record-keeping practices but said that "this FDA investigation could not proceed to any definitive resolution," because of "problems/barriers that were encountered throughout the inspection."

__ In October of 2002, the FDA received new reports that two patients at a Rochester, N.Y., hospital came down with symptoms of bacterial meningitis after receiving a different NECC injection. The steroid, methylprednisolone acetate, is the same injectable linked to the current outbreak and is typically is used to treat back pain. Both patients were treated with antibiotics and eventually recovered, according to FDA documents cited by the committee.

When officials from the FDA and Massachusetts Board of Pharmacy visited NECC later in the month, Cadden said vials of the steroid returned by the hospital had tested negative for bacterial contamination. But when FDA scientists tested samples of the drug collected in New York they found bacterial contamination in four out of 14 vials sampled. It is not entirely clear whether FDA tested the same lot shipped to the Rochester hospital.

__ At a February 2003 meeting between state and federal officials, FDA staff emphasized "the potential for serious public consequences if NECC's compounding practices, in particular those relating to sterile products, are not improved." The agency issued a list of problems uncovered in its inspection to NECC, including a failure to verify if sterile drugs met safety standards.

But the agency decided to let Massachusetts officials take the lead in regulating the company, since pharmacies are typically regulated at the state level. It was decided that "the state would be in a better position to gain compliance or take regulatory action against NECC as necessary," according to a summary of the meeting quoted by investigators.

The FDA recommended the state subject NECC to a consent agreement, which would require the company to pass certain quality tests to continue operating. But congressional investigators say Massachusetts Board of Pharmacy did not take any action until "well over a year later."

__ In October 2004, the board sent a proposed consent agreement to Cadden, which would have included a formal reprimand and a three-year probationary period for the company's registration. The case ended without disciplinary action in 2006, when NECC agreed to a less severe consent decree with the state.

Massachusetts officials indicated Tuesday they are still investigating why NECC escaped the more severe penalty.

"I will not be satisfied until we know the full story behind this decision," the state's interim health commissioner Lauren Smith said in a transcript of her prepared testimony released a day ahead of delivery. Smith is one of several witnesses scheduled to testify Wednesday, including FDA Commissioner Margaret Hamburg.

The committee will also hear from the widow of 78-year-old Eddie C. Lovelace, a longtime circuit court judge in southern Kentucky. Autopsy results confirmed Lovelace received fungus-contaminated steroid injections that led to his death Sept. 17.

Joyce Lovelace will urge lawmakers to work together on legislation to stop future outbreaks caused by compounded drugs, according to a draft of her testimony.

"We now know that New England Compounding Pharmacy, Inc. killed Eddie. I have lost my soulmate and life's partner with whom I worked side by side, day after day for more than fifty years," Lovelace states.

Barry Cadden is also scheduled to appear at the hearing, after lawmakers issued a subpoena to compel him to attend.

The NECC has been closed since early last month, and Massachusetts officials have taken steps to permanently revoke its license. The pharmacy has recalled all the products it makes, including 17,700 single-dose vials of a steroid that tested positive for the fungus tied to the outbreak.

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Who's who in the Petraeus scandal

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What started out as a leisurely stroll through the Philadelphia Museum of Art on Nov. 11 with his girlfriend, quickly turned into quite a surreal experience for Max Galuppo, 20, of Bloomsbury, N.J. Galuppo, a Temple University student, found his doppelganger in a 16th century...
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Dalai Lama wants thorough probe into Tibet deaths

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TOKYO (AP) — Lashing back at criticism from Beijing, the Dalai Lama on Tuesday said China needs to thoroughly investigate the causes of self-immolations by Tibetans and blamed "narrow-minded Communist officials" for seeing Buddhist culture as a threat.

The Dalai Lama also called on foreign media and members of Japan's parliament to visit Tibet — though such trips are severely restricted — to see that what is happening there does not go ignored.

"I always ask the Chinese government, please, now, thoroughly investigate," the Tibetan Buddhist leader said. "What is the cause of these sad things?"

The Dalai Lama was speaking to a group of Japanese lawmakers that included opposition party head Shinzo Abe, an outspoken China hawk seen by many as the top contender to become the country's next prime minister.

Chinese Foreign Ministry spokesman Hong Lei said Beijing has lodged a protest with Japan following the Dalai Lama's visit.

"China is opposed to any country or any individual providing a stage for his separatist moves," Hong said.

Eight self-immolations have been reported over six days in China's Tibetan region, including two on Monday. China has long accused the Dalai Lama and his supporters of inspiring and even glorifying such acts, though the Dalai Lama says he opposes all violence.

Hong had launched a new salvo at the Dalai Lama on Monday, claiming he was taking Japan's side in an ongoing territorial dispute and calling him a separatist who is aligning with Japanese right-wingers.

Chinese media said the Dalai Lama called the islands by their Japanese name during a news conference in Yokohama last Monday, but an Associated Press review of a tape of the event showed he referred to them only as "the islands."

Tibet support groups overseas say the increase in protests in recent days is meant to highlight Tibetan unhappiness with Chinese rule as the country's leaders hand over power to younger successors at a party congress in Beijing.

The Dalai Lama has said the self-immolations are a symptom of the desperation and frustration felt by Tibetans living under the Chinese government's hardline policies in the region, including tight restrictions on religious life.

The Dalai Lama fled to India following an abortive 1959 uprising against Chinese rule over Tibet. He denies seeking the region's independence, saying that he wishes Tibetans to enjoy real autonomy and protection of their traditional Buddhist culture.

In his remarks Tuesday, he said China's top leaders may not realize the severity of that frustration because "narrow-minded Communist officials" on the ground fear Tibetan Buddhist culture and may not be relaying the real situation to Beijing.

"These officials on the spot may not reply clearly to the higher authority," he said, suggesting that foreign media and lawmakers should go to Tibet to see the situation there and share it with the outside world.

Access to Tibet is controlled by regional security services and is permanently off limits to foreign journalists, except when the government grants special access. Such access has become increasingly rare in recent years as Beijing seeks to maintain tight control over the story and prevent detailed reporting on unrest.

Since anti-government riots in 2008, access even to traditionally Tibetan areas in provinces neighboring the Tibetan Autonomous Region has been tightly restricted. The vast majority of the self-immolations have taken place in such areas, often near large monastic communities, and authorities have responded with a smothering police presence.

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Associated Press writers Christopher Bodeen and Louise Watt in Beijing contributed to this report.

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Lakers intrigued by chance to play for D’Antoni

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EL SEGUNDO, Calif. (AP) — Pau Gasol got home from the game and read about it on Twitter, while Dwight Howard got a midnight message on his BlackBerry. They shared most Los Angeles Lakers fans’ mix of surprise, trepidation and anticipation.


Just when everybody thought the Lakers were getting back together with Phil Jackson, they switched course in the middle of the night and went with Mike D’Antoni.













What a weekend in Hollywood — and the real drama isn’t over yet.


The Lakers reacted with ample excitement and a little bewilderment Monday to their front office’s surprising decision to hire D’Antoni as coach Mike Brown’s replacement over Jackson, the 11-time champion who discussed the job at his home Saturday and apparently wanted to return. D’Antoni didn’t even interview for the job in person, speaking to the Lakers over the phone.


“It has been crazy, but all this stuff will just make this team stronger,” said Howard, who has been in a Lakers uniform for about six weeks. “Everything that we’ve been through so far, it’s going to make us stronger, and we have to look at this as a positive situation.”


The Lakers’ third coach in four days won’t take over the team until later in the week. D’Antoni still hadn’t been cleared to travel Monday after undergoing knee replacement surgery earlier in the month, although the Lakers are optimistic the former Knicks and Suns coach will arrive in Los Angeles on Wednesday.


So interim coach Bernie Bickerstaff was still in charge Monday when the Lakers gathered for an informal workout ahead of Tuesday’s game against San Antonio. Just two weeks into the regular season, the Lakers (3-4) are about to start over with a new offense and another coaching staff — and a renewed certainty they’re expected to compete for a title this season.


“It’s been a zoo,” said forward Antawn Jamison, a 15-year NBA veteran who played for D’Antoni on a U.S. national team. “But as I was telling somebody, it’s just a typical day here in L.A. It’s interesting. … It should be a lot easier to adjust to than the system we were trying to get adjusted to early on in the season. We’ve got Steve (Nash) that can help us out.”


Two Lakers who supported both Brown and his two potential replacements weren’t available in El Segundo to weigh in on the hire. Nash missed the workout while getting treatment on his injured leg, while Kobe Bryant left before it ended to share a helicopter ride back home to Orange County with point guard Steve Blake, who needed an exam on his abdominal injury.


And the tall, professorial coach with all the rings wasn’t at the Lakers’ training complex at all.


Just 24 hours after Jackson seemed headed back to his oversized chair on the Staples Center bench, D’Antoni had the job.


It’s too soon to tell how the Buss family’s latest counterintuitive move will sit with Lakers fans, who chanted “We want Phil!” during the club’s weekend games, both victories after a 1-4 start.


“I think everybody had expectations about it, and they were all pretty high,” Gasol said of Jackson’s potential return. “We all understood what Phil brings to the table … and what he means to the city and the franchise. It just couldn’t work out for whatever reason.”


Jackson issued a statement to a handful of media outlets Monday, implying he was essentially offered the job after meeting with Lakers owner Jim Buss and general manager Mitch Kupchak. Jackson thought he would be able to come back to the Lakers on Monday with his decision, but instead was awakened by a midnight phone call from Kupchak.


“The decision is of course theirs to make,” Jackson said in his statement. “I am gratified by the groundswell of support from the Laker fans who endorsed my return, and it is the principal reason why I considered the possibility.”


The Lakers largely echoed the thoughts of Howard, who was looking forward to playing for Jackson: “Management had to do what they felt is best for the team, and we as players have got to find a way to win.”


The Lakers publicly offered no reason for passing over the coach with the most championships in NBA history. Although nobody could claim the Buss family is afraid of spending money, Brown is still owed well over $ 10 million for the remaining three seasons on his four-year, $ 18 million contract, while D’Antoni will make $ 4 million a season for the next three years — and their salaries together might be less than what Jackson would command.


The Lakers largely know what they would get with Jackson, but D’Antoni intrigues this older, top-heavy team with an urgency to contend for a title before Howard’s free agency next summer and Bryant’s possible retirement in a few years.


Howard and Gasol both believe D’Antoni’s up-tempo style can work well for the Lakers. Howard would seem to be a natural to partner with Nash in the pick-and-roll attacks loved by D’Antoni and Nash, although Gasol doesn’t immediately fit into the definition of a big man who can play on the perimeter and shoot 3-pointers.


“It’s a great system, (but) I don’t think he ever had a defender such as myself or a defender such as Dwight Howard on those teams,” Metta World Peace said. “I don’t think he ever coached those type of players, so his defense should be self-explanatory, and his offense is amazing, so it should be fun for Laker fans.”


The rest of the NBA sat back and watched the Lakers’ drama with amusement over the past two days, with Dallas owner Mark Cuban weighing in gleefully on the mess: “I hope they have to do it again and again and again.”


Jackson’s flirtation with the job is the strongest indication yet that he’s interested in coaching again, which makes him a prime candidate for another franchise. Yet D’Antoni also received praise around the league — even from New York, where he resigned last March after failing to win a playoff game in four years with the Knicks.


“Despite all the hoopla … that was going on about me and Mike, we actually have a pretty good relationship, especially behind closed doors,” Carmelo Anthony said. “We actually talked a lot, talked basketball. Hopefully he brings some positive energy over there. Anytime guys are losing like that, there’s always negativity, a lot of negative energy. So sometimes change is better.”


Added Dwyane Wade, who has played for D’Antoni on the U.S. national team: “He has a tough job ahead of him, but I’m sure he’s excited about the opportunity that he gets to be with America’s team.”


___


AP Sports Writers Brian Mahoney and Chris Duncan contributed to this report.


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'Skyfall' brings record Bond debut of $88.4M

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LOS ANGELES (AP) — James Bond is cashing in at the box office.

"Skyfall," the 23rd film featuring the British super-spy, pulled in a franchise-record $88.4 million in its U.S. debut, bringing its worldwide total to more than $500 million since it began rolling out overseas in late October.

The top 20 movies at U.S. and Canadian theaters Friday through Sunday, followed by distribution studio, gross, number of theater locations, average receipts per location, total gross and number of weeks in release, as compiled Monday by Hollywood.com are:

1. "Skyfall," Sony, $88,364,714, 3,505 locations, $25,211 average, $90,564,714, one week.

2. "Wreck-It Ralph," Disney, $33,012,796, 3,752 locations, $8,799 average, $93,647,405, two weeks.

3. "Flight," Paramount, $14,785,097, 2,047 locations, $7,223 average, $47,455,396, two weeks.

4. "Argo," Warner Bros., $6,617,229, 2,763 locations, $2,395 average, $85,583,187, five weeks.

5. "Taken 2," Fox, $4,012,829, 2,487 locations, $1,614 average, $131,300,000, six weeks.

6. "Cloud Atlas," Warner Bros., $2,658,250, 2,023 locations, $1,314 average, $22,844,956, three weeks.

7. "The Man With the Iron Fists," Universal, $2,592,705, 1,872 locations, $1,385 average, $12,821,030, two weeks.

8. "Pitch Perfect," Universal, $2,573,350, 1,391 locations, $1,850 average, $59,099,993, seven weeks.

9. "Here Comes the Boom," Sony, $2,522,790, 2,044 locations, $1,234 average, $39,033,885, five weeks.

10. "Hotel Transylvania," Sony, $2,400,226, 2,566 locations, $935 average, $140,954,208, seven weeks.

11. "Paranormal Activity 4," Paramount, $1,980,033, 2,348 locations, $843 average, $52,600,612, four weeks.

12. "Sinister," Summit, $1,524,448, 1,554 locations, $981 average, $46,578,686, five weeks.

13. "Silent Hill: Revelation," Open Road Films, $1,300,137, 1,902 locations, $684 average, $16,383,406, three weeks.

14. "The Perks of Being a Wallflower," Summit, $1,132,924, 607 locations, $1,866 average, $14,614,770, eight weeks.

15. "Lincoln," Disney, $944,308, 11 locations, $85,846 average, $944,308, one week.

16. "Alex Cross," Summit, $911,973, 1,090 locations, $837 average, $24,603,042, four weeks.

17. "Fun Size," Paramount, $757,223, 1,301 locations, $582 average, $8,800,336, three weeks.

18. "Looper," Sony, $582,150, 491 locations, $1,186 average, $64,669,383, seven weeks.

19. "The Sessions," Fox, $545,550, 128 locations, $4,262 average, $1,655,222, four weeks.

20. "Seven Psychopaths," CBS Films, $404,812, 356 locations, $1,137 average, $14,098,469, five weeks.

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Universal and Focus are owned by NBC Universal, a unit of Comcast Corp.; Sony, Columbia, Sony Screen Gems and Sony Pictures Classics are units of Sony Corp.; Paramount is owned by Viacom Inc.; Disney, Pixar and Marvel are owned by The Walt Disney Co.; Miramax is owned by Filmyard Holdings LLC; 20th Century Fox and Fox Searchlight are owned by News Corp.; Warner Bros. and New Line are units of Time Warner Inc.; MGM is owned by a group of former creditors including Highland Capital, Anchorage Advisors and Carl Icahn; Lionsgate is owned by Lions Gate Entertainment Corp.; IFC is owned by AMC Networks Inc.; Rogue is owned by Relativity Media LLC.

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Online:

http://www.hollywood.com

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British medical journal slams Roche on Tamiflu

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LONDON (AP) — A leading British medical journal is asking the drug maker Roche to release all its data on Tamiflu, claiming there is no evidence the drug can actually stop the flu.

The drug has been stockpiled by dozens of governments worldwide in case of a global flu outbreak and was widely used during the 2009 swine flu pandemic.

On Monday, one of the researchers linked to the BMJ journal called for European governments to sue Roche.

"I suggest we boycott Roche's products until they publish missing Tamiflu data," wrote Peter Gotzsche, leader of the Nordic Cochrane Centre in Copenhagen. He said governments should take legal action against Roche to get the money back that was "needlessly" spent on stockpiling Tamiflu.

Last year, Tamiflu was included in a list of "essential medicines" by the World Health Organization, a list that often prompts governments or donor agencies to buy the drug.

Tamiflu is used to treat both seasonal flu and new flu viruses like bird flu or swine flu. WHO spokesman Gregory Hartl said the agency had enough proof to warrant its use for unusual influenza viruses, like bird flu.

"We do have substantive evidence it can stop or hinder progression to severe disease like pneumonia," he said.

In the U.S., the Centers for Disease Control and Prevention recommends Tamiflu as one of two medications for treating regular flu. The other is GlaxoSmithKline's Relenza. The CDC says such antivirals can shorten the duration of symptoms and reduce the risk of complications and hospitalization.

In 2009, the BMJ and researchers at the Nordic Cochrane Centre asked Roche to make all its Tamiflu data available. At the time, Cochrane Centre scientists were commissioned by Britain to evaluate flu drugs. They found no proof that Tamiflu reduced the number of complications in people with influenza.

"Despite a public promise to release (internal company reports) for each (Tamiflu) trial...Roche has stonewalled," BMJ editor Fiona Godlee wrote in an editorial last month.

In a statement, Roche said it had complied with all legal requirements on publishing data and provided Gotzsche and his colleagues with 3,200 pages of information to answer their questions.

"Roche has made full clinical study data ... available to national health authorities according to their various requirements, so they can conduct their own analyses," the company said.

Roche says it doesn't usually release patient-level data available due to legal or confidentiality constraints. It said it did not provide the requested data to the scientists because they refused to sign a confidentiality agreement.

Roche is also being investigated by the European Medicines Agency for not properly reporting side effects, including possible deaths, for 19 drugs including Tamiflu that were used in about 80,000 patients in the U.S.

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Online:

www.bmj.com.tamiflu/

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